https://nutritionandmetabolism.biomedcentral.com/articles/10.1186/s12986-016-0129-3
Subscribe to:
Post Comments (Atom)
-
Obstructive sleep apnea (OSA) is one of the most common sleep disorders in North America, affecting approximately 15-30% of men and 10-15% o... -
Alright, so this blog post is a bit long, but I loved this couple, and his story is pretty typical for people dealing with chronic heart f... -
It seems almost a right of passage in ones life to be asked the hypothetical “If your friends jumped off a bridge, would you...
As an avid diet coke consumer, I always find it interesting to read studies about the health benefits or consequences that diet soda or non-sugar sweeteners have on the body. I found another article that discusses the impact that acute consumption of diet soda has on the brain's response to food cues. In this controlled, cross-over study, researchers found that diet soda increases activation of reward-related insula and caudate and decreases activation of the cognitive control-related DLPFC. The combination of these occurrences offers an argument for diet soda contributing to obesity through increased perceived food palatability.
ReplyDeleteThis study was incredibly interesting because we often think of anything associated with "diet" being healthier or better for our body. Obviously, more research can always be done, but there has been alot of science found that I need to find a healthier drink option!!
Farr, O. M. (2021). Acute diet soda consumption alters brain responses to food cues in humans: A randomized, controlled, cross-over pilot study. Nutrition and Health, 27(3), 295–299. https://doi.org/10.1177/0260106021993753
DeleteHi Cass! I thought this post was very interesting! I, myself, am not an avid soda drinker (or even diet soda drinker for that matter), but there are a number of people in my life that rely on diet soda whenever they have dinner (like going out and such). And it’s funny because, diet soda is marketed to be “better” and “healthier” than the average soda, yet some are filled with artificial sweeteners (that some say don’t count as real sugar) in order to have that same taste. I wanted to look a bit more into artificial sweeteners because of this! I found a study titled “Consumption of Diet Soda Sweetened with Sucralose and Acesulfame-Potassium Alters Inflammatory Transcriptome Pathways in Females with Overweight and Obesity,” and they aimed at identifying molecular pathways in adipose impacted by LCSs [low-calorie sweeteners] (Sylvetsky 2020), some of which may be present in various diet sodas. They noted that most human intervention studies have assessed effects of prolonged LCS consumption on body weight, rather than on other metabolic outcomes, such as alterations in glucose/insulin homeostasis or systemic inflammation, which are central to the development of cardiometabolic disease (Sylvetsky 2020). I think this is one of the first studies that really looks at LCS and adipose gene expression! In their study (which, I do have to say, involves a small study group) they found that consumption of commercially available, caffeine-free diet soda sweetened with sucralose and Ace-K three times daily for 8 weeks altered the transcripts of key immune molecules and inflammatory pathways in adipose tissue and also affected genes involved in heme biology in young adult women with overweight or obesity (Sylvetsky 2020) and their findings also demonstrated that 8 weeks of sucralose and Ace-K ingestion dysregulates inflammatory pathways in adipose tissue, which highlights tissue-specific differences in responses to sucralose exposure (Sylvetsky 2020). They concluded that disturbances in adipose-derived immune mediators may in part explain cardiometabolic impairments associated with diet soda consumption in observational studies (Sylvetsky 2020). At the end of the day soda, whether it be diet or not, is just not a good choice for your body, and although more studies need to be done on artificial sweeteners and their affects (especially ones that look at both males and females, as well as larger control groups), this is enough for me to pass up the next diet coke I may be offered! What do you think?
ReplyDeleteSylvetsky, Allison C., et al. “Consumption of Diet Soda Sweetened with Sucralose and Acesulfame‐Potassium Alters Inflammatory Transcriptome Pathways in Females with Overweight and Obesity.” Molecular Nutrition & Food Research, vol. 64, no. 11, 2020, p. 1901166. Crossref, doi:10.1002/mnfr.201901166.